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The PVA can be considered as a kind of polymerized water and this aspect is the basis
of its generally accepted excellent biocompatibility |
The gelling of the injectable PVA happens in situ and is the result of a purely physical
process, no chemical reactions nor side products are involved |
The InnoGEL technology is unique in combining injectability with a physical in situ gellation
mechanism |
The PVA gel shows superior mechanical properties which surpass the mechanical properties
of classical PVA gels and any other gels proposed in the field of nucleus replacement |
Extrusion of implanted gels is known to be the central failure mode in the field of nucleus
replacement, but heavy duty biomechanical test with the InnoSpine gel implanted in
isolated human intervertebral disks showed no extrusion at all |
- R&D |